Pitavastatin Calcium

Description:

API Nomen Indicium Specification US DMF EU DMF CEP
Pitavastatin Calcium Hypercholesterolemia In-Domus      


Product Detail

Product Tags

Product SINGULA

匹伐 他 汀钙 Pitavastatin 147526-32-7 In-Domus
PI-5 3800-06-4 In-Domus
PI-6 145516-11-4 In-Domus
PI-7 121660-11-5 In-Domus

 

Descriptio

Pitavastatin calcium (hemicalcium NK-104) hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor est potentior.Pitavastatin Calcium (NK-104 hemicalcium) vetat synthesin cholesterol ab acetico acetico cum IC50 ex 5.8 nM in cellulis HepG2.Pitavastatin Calcium est hepatocytum humilis densitatis lipoprotein-cholesterol (LDL-C) receptor efficientis inducentis.Cancri anti- actio.

 

Background

Pitavastatin Calcium inhibitor competitive est enzyme HMGCR (HMG-CoA reductase) reductionem in synthesi cholesteroli LDL.Studia alterna ostendunt pitavastatin productionem oxygenii supprimi posse in cellulis endothelialibus, inhibitione oxidasi NADPH.Praeterea pitavastatin expressionem eNOS mRNA minuit dum responsio dependens NO augens ab acetylcholino ac calcii ionophore excitata, A23187.Praeterea, pitavastatin impedit regulam conductionis calcii-canales potassium effectae per gradus cholesteroli in cellulis demisso.

 

Repono

4°C, defendat a lumine

*In solvendo: -80°c, menses VI;-20°C, 1 mensis (protegat a luce)

 

Chemical structure

Pitavastatin Calcium

Related Biological Data

Pitavastatin Calcium2

CERTIFICATE

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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